Background and Aim: The Pyrus Biossieriana Bushe tree (Telka) belongs to
Materials and: This was an experimental study. HeLa cells were cultured under standard conditions in the culture RPMI 1640 in 24-well plates. Then, the Telka leaf extract was added to the
Findings: Study findings revealed that the Telka leaf extract is cytotoxic at doses of 2% and higher. The differences between the less-than-2% doses of the extract and the control group were not statistically significant. The antioxidative power of the control group significantly differed from the “Telka leaf extract + tert-butyl hydroperoxide” group (P value = 0.001). After adding tert-butyl hydroperoxide, the Ferric Reducing Antioxidant Power was significantly reduced compared with the control group.
Conclusion: Pre-incubation of cells at different doses of the Telka leaf extract increases the total activity of the culture. Consequently, this extract can be used as a natural antioxidant.
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